TP383 - Alimentos, Obesidade, Inflamação e Cognição - 1S/2018 Imprimir

Ementa:

A disciplina aborda o efeito dos alimentos funcionais e das substâncias bioativas na obesidade, na inflamaçao e na cognição. São endereçados seus mecanismos de ação contra obesidade, suas comorbidades, colite ulcerativa, Doença de Chron, Mal de Alzheimer, Diabetes tipo III e na melhora da cognição.

Bibliografia:

Referências básicas:

• Nile SH, Park SW. Edible berries: Bioactive components and their effect on human health. Nutrition. 2014;30:134-44
• Emmerzaal TL, Kiliaan AJ, Gustafson DR. 2003-2013: A Decade of Body Mass Index, Alzheimer's Disease, and Dementia. Journal of Alzheimer's Disease. 2015;43:739-55
• Spencer, JPE;  Rhodes, JS;  Rendeiro, C. The mechanisms of action of flavonoids in the brain: Direct versus indirect effects. Neurochemistry International. Nutraceuticals: Molecular and Functional Insights into how Natural Products Nourish the Brain. Volume 89, October 2015, Pages 126–139
• Pan, M-H; Wu, J-C; Lai, C-S. Molecular mechanism on functional food bioactives for anti-obesity. Current Opinion in Food Science, Volume 2, April 2015, Pages 9–13.
• Yamamoto, T., M. Nakahigashi, and A.R. Saniabadi, Review article: diet and inflammatory bowel disease--epidemiology and treatment. Aliment Pharmacol Ther, 2009. 30(2): p. 99-112.
• Hur, S.J., et al., Review of natural products actions on cytokines in inflammatory bowel disease. Nutr Res, 2012. 32(11): p. 801-16.
• Reynolds, A, Mann, J; Cummings, J; Winter, M, Mete E, Morenga, L. THE LANCET. 393 (10170), P434-445, 2019. Carbohydrate quality and human health: a series of systematic reviews and meta-analyses. DOI:https://doi.org/10.1016/S0140-6736(18)31809-9.
• Bioactive Compounds Health Benefits and Potential Applications, Edited by Maira Rubi Segura Campos, ISBN (print): 978-0-12-814774-0, ISBN (online): 978-0-12-814775-7, 2019
• Phenolics and polyphenolics in foods, beverages and spices: Antioxidant activity and health effects –A review, Fereidoon Shahidi, Priyatharini Ambigaipalan, journal of functional foods 18 ( 2 0 1 5 ) 820–897
• Cazarin, CBB; Bicas, JL; Pastore, GM; Marostica Junior, MR. Bioactive Food Components Activity in Mechanistic Approach, Academic Press, 2022, https://doi.org/10.1016/B978-0-12-823569-0.00013-8. Paperback ISBN:  9780128235690; eBook ISBN: 9780128225905

Referências Complementares:

• Abreu, M.T., Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function (vol 10, pg 131, 2010). Nature Reviews Immunology, 2010. 10(3): p. 131-144.
• Hendrickson, B.A., R. Gokhale, and J.H. Cho, Clinical Aspects and Pathophysiology of Inflammatory Bowel Disease. Clinical Microbiology Reviews, 2002. 15(1): p. 79-94.
• Hamer, H.M., et al., Review article: the role of butyrate on colonic function. Aliment Pharmacol Ther, 2008. 27(2): p. 104-19.
• de la Monte SM, Wands JR. Alzheimer's disease is type 3 diabetes-evidence reviewed. J Diabetes Sci Technol. 2008;2:1101-13
• Williams RJ, Spencer JPE. Flavonoids, cognition, and dementia: Actions, mechanisms, and potential therapeutic utility for Alzheimer disease. Free Radical Bio Med. 2012;52:35-45
• Dragano NRV, Marques AC, Cintra DEC, Solon C, Morari J, Leite-Legatti AV, et al. Freeze-dried jaboticaba peel powder improves insulin sensitivity in high-fat-fed mice. British Journal of Nutrition. 2013;110:447-55
• Batista AG, Lenquiste SA, Cazarin CBB, da Silva JK, Luiz-Ferreira A, Bogusz S, et al. Intake of jaboticaba peel attenuates oxidative stress in tissues and reduces circulating saturated lipids of rats with high-fat diet-induced obesity. Journal of Functional Foods. 2014;6:450-61.
• Correia SC, Santos RX, Carvalho C, Cardoso S, Candeias E, Santos MS, et al. Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation. Brain Res. 2012;1441:64-78.
• Chen T-Y, Kritchevsky J, Hargett K, Feller K, Klobusnik R, Song BJ, et al. Plasma bioavailability and regional brain distribution of polyphenols from apple/grape seed and bilberry extracts in a young swine model. Molecular Nutrition & Food Research. 2015;59:2432-47.
• Henriksen, E. J., Diamond-Stanic, M. K., & Marchionne, E. M. (2011). Oxidative stress and the etiology of insulin resistance and type 2 diabetes. Free Radical Biology & Medicine, 51, 993–999. Journal of Sport and Health Science, 2, 81-86.
• Ulcerative colitis: Gut microbiota, immunopathogenesis and application of natural products in animal models, Roberto de Paula do Nascimento, Ana Paula da Fonseca Machado, Julio Galvez, Cinthia Baú Betim Cazarin, Mario Roberto Maróstica Junior, Life Sciences 258 (2020) 118129
• Polyphenols from food by-products: An alternative or complementary therapy to IBD conventional treatments, Ana Paula da Fonseca Machado, Marina Vilar Geraldi, Roberto de Paula do Nascimento, Amanda Maria Tomazini Munhoz Moya, Teresa Vezza, Patricia Diez-Echave, Julio Juan Galvez, Cinthia Bau Betim Cazarin, Mario Roberto Marosti

Ano de Catálogo: 2018

Créditos: 4